The accident happened at about 6am when the man was thrown from his Kawasaki motorcycle in a collision with a Holden Commodore at the intersection of Martin and Brinkley roads.

Police said the 61-year-old male Commodore driver, from Murray Bridge, was not injured in the collision.

The death was the fourth in the Murray Mallee since Sunday and the ninth since January.

While the State’s road toll has yet to reach last year’s total of 45, police say they will be out in force during the five-day Easter holiday weekend.

The RAA has warned people to be aware of the dangers on the road, especially leading into the long weekend.

RAA managing director Ian Stone said 30 per cent of all crashes on South Australian roads were caused by fatigue, which, on average, resulted in 18 fatalities and 142 injuries each year.

“Make no mistake, tiredness is a killer on our roads,” he said.

“Research has shown that being awake for 17 hours straight produces the same level of driving impairment as a blood alcohol level content of 0.05 and doubles your risk of being involved in a crash.

“Fatigue severely affects reaction times, concentration and decision making skills that are critical for being able to drive a vehicle safely.

“The drive now, sleep later, attitude is incredibly dangerous - not just to the tired driver but to all road users.”

Volunteer groups will also be out in force, giving up their holidays to operate 17 Driver Reviver sites across the State during the long weekend.

- Details: Major crash investigators are asking for anyone who witnessed the accident in Murray Bridge on Thursday to contact BankSA Crime Stoppers on 1800 333 000 or online at www.sa. crimestoppers.com.au.