At about 2.20pm CFS and MFS firefighters responded to a car fire on the up-track of the South Eastern Freeway at Crafers West.
A four-wheel drive and campervan were fully involved with fire when emergency services arrived.
The two occupants were able to evacuate from the vehicle without reporting injury.
The vehicle and campervan was completely destroyed.
The estimated damage bill is $80-$90,000.
The cause is currently unknown.